CoQ10 is naturally produced by your body and plays a key role in maintaining your overall health, supporting healthy blood sugar levels, mitochondrial function, and brain health.
CoQ10 supplements can treat a variety of diseases, and low levels have been associated with a variety of medical conditions. Since levels drop as you age, it’s important to supplement with CoQ10 on a regular basis.
Below, you’ll find the best CoQ10 supplements, ranked and reviewed by our expert health team.
1. HeathWise CoQ10
HealthWise’s 100% natural supplement provides 240 mg of elite CoQ10 per serving without any artificial ingredients. It also promotes healthy joints and immune system responses.
What we like: HeathWise CoQ10 works on a molecular level to improve your cellular energy production and support healthy blood sugar levels. It’s also free of most common allergens, GMOs, and is made in the USA to maximize purity.
Flaws: This CoQ10 doesn’t absorb as quickly as others, which may put some people off. Regardless, it’s our #1 pick of 2020.
2. Essential Elements
Essential Elements CoQ10 is 2.6X more absorbable and will help you maintain a healthy immune function. It contains no GMOs, gluten, dairy, or preservatives.
What we like: With its patented formula, Essential elements delivers a powerful coq10 supplement that has high bioavailability and supports your brain, heart, and vascular system.
Flaws: This supplement help improve exercise capacity as much as other supplements.
3. Qunol Ultra
Qunol Ultra provides 3X better absorption than regular CoQ10, and is 100% water and fat-soluble. It contains no additives, colors, or preservatives.
What we like: QuNol Ultra is the #1 recommended form of CoQ10 by Cardiologists. Since it comes in soft gels, it’s easy to swallow – making it easier to experience the benefits. It can also help rebuild the CoQ10 lost from statin drug users.
Flaws: This CoQ10 supplement doesn’t improve your blood pressure as much as others.
4. Doctor’s Best High Absorption
Doctor’s Best CoQ10 supplement will support brain health, immune performance, skin health, exercise capacity, gum health, and more. It’s easily absorbed and supports your cardiovascular health.
What we like: Formulated with Bioperine to improve absorption, this natural black pepper extract helps to restore your body’s depleted CoQ10 swiftly and efficiently; which is especially beneficial for older folks and those currently taking statin drugs.
Flaws: The dose per capsule might be underwhelming for some and this supplement isn’t known for improving headaches or migraines.
5. Qunol Mega Ubiquinol
Qunol Mega Ubiquinol is designed to provide fast absorption so that you can reap the benefits quickly. It’s patented formula makes it 100% water-soluble and fat-soluble. It’s also important for the production of energy produced by our cells.
What we like: Qunol provides the #1 cardiologist recommended CoQ10. This includes 100mg of Ubiquinol per serving to help saturate your body as quickly as possible without overloading it.
Flaws: While it can be found cheaper, this product isn’t as good as Qunol Ultra.
6. Nature’s Made
Nature’s Made provides 200mg of CoQ10 per serving, ensuring that even the most deficient individual can safely and quickly replenish their levels.
What we like: Nature’s Made CoQ10 will help support your cellular energy production and heart function. It contains a 40 days supply of 200mg of CoQ10 per serving, making it one of the best bang for your buck products on the market.
Flaws: The bioavailability in this supplement is not as good as others.
7. Puritan’s Pride
Puritans Pride will help support a healthy heart and cardiovascular functioning. It contains 100mg of CoQ10 per serving, making it great for newer users.
What we like: Puritan’s Pride CoQ10 provides rapid release soft gels that are easy to swallow. This allows for quick absorption of CoQ10, ensuring that you can receive the benefits as quickly as possible.
Flaws: This supplement doesn’t help combat aging as effectively as others.
8. SmartyPants Women’s Formula
SmartyPants Women’s Formula provides 17 essential nutrients, including vitamin D3 for immune health, vitamin B12 for energy, vitamin K for bones, and vitamin E for antioxidant support. Omega 3’s are also included.
What we like: SmartyPants Women’s Formula includes extra premium ingredients, including beta carotene, vitamin B6, vitamin K12, and choline. These gummy vitamins also include Biotin for women to help them maintain healthy hair, skin, and nails, and iodine for thyroid support.
Flaws: This supplement is only for women and fails to provide the proper nutrients and dosages for men’s bodies.
8. Foxxy Doc
Foxxy Doc provides 200 mg of CoQ10, making it ideal for more experienced users. It’s highly absorbable, providing fast cellular energy to your heart and brain.
What we like: This product will help increase your cognitive function, energy, and endurance. It also slows down the effects of aging. It’s made without any junk fillers, and only contains natural ingredients.
Flaws: You won’t see much muscle pain support.
10. Kirkland Signature
Kirkland Signature CoQ10 is highly potent, making it an excellent option to support your heart, blood pressure, and brain. It’s also great for supporting maximum energy production.
What we like: Kirkland Signature provides one of the highest potency CoQ10 supplements on the market with 300mg per serving. It has no artificial colors and comes in an easy to swallow soft gel formula.
Flaws: The absorption in this supplement could be faster.
Who Needs CoQ10?
Your body naturally produces CoQ10, but if you’re low in this nutrient, it can cause a multitude of problems in your body. Low levels have been shown to put you at risk for degenerative diseases, such as Alzheimer’s, Huntington’s, and cardiovascular disease. Because your levels naturally decline as you age, it makes sense to that people over the age of 35 should look into supplementing with it regularly to restore their levels.
CoQ10 can treat people who are prone to headaches and migraines. CoQ10 is also a beneficial supplement to take if you’re on a statin prescription. Statin, a medication that lowers your cholesterol, lowers your CoQ10 levels, and taking a CoQ10 supplement can balance this drawback.
CoQ10 can also improve your skin health, physical performance, and muscle pain, so even if you’re not deficient in this nutrient, your body may benefit from it. People on medication, especially chemotherapy drugs and blood pressure mediation, should be careful with CoQ10 as it may negatively interact with these medications.
Pregnant, nursing women, and children shouldn’t supplement with CoQ10 unless otherwise directed by a healthcare professional.
How We Ranked
One of the first things we looked at when ranking the best CoQ10 supplements on the market was the absorption and bioavailability. Bioavailability refers to how much of a substance actually gets absorbed and used by your body. As such, products with high bioavailability provided the most powerful doses and best bang for your buck. This is a main reason why Essential Elements was our #1 pick CoQ10, being 2.6X more absorbable. Qunol Ultra also ranked in the top 5 because it’s absorption is better than standard CoQ10.
CoQ10 is well known for providing a multitude of benefits, including improving cellular energy, and managing blood sugar levels. Kirkland sneaked its way on our list for the very reason that it gives you more energy. Nature’s Made also made the list for providing superior CoQ10 that focuses on your body’s natural enhancing cellular energy production.
Top-tier CoQ10 will also improve your exercise performance and improve your skin health. Doctor’s Best High Abortion ranked in the middle of our list because it gives you a broad range of benefits ranging from better brain health, skin health, and exercise capacity.
Lastly, we looked at purity and dosage. In general, we preferred products that contained 200mg or less per serving as this allowed for better dose-tailoring. We also preferred products that contained no common allergens, GMOs, preservatives, and artificial ingredients. Companies that provided third-party lab testing results were a bonus.
CoQ10 may help protect your lungs. Lung damage can be brought on by poor protection from antioxidants and excessive oxidative stress in your lungs. Asthma, chronic pulmonary disease (COPD), and other lung diseases can arise because of this.
One study, involving 41 patients ranging from 25-50 years of age who suffered from persistent to moderate asthma, showed that corticosteroids were reduced after CoQ10 supplementation (1).
Another study found that CoQ10 levels are linked to the degree of oxidative stress. After researching individuals with chronic pulmonary disease (COPD), people with lower CoQ10 levels showed an increase in oxidative stress (2).
CoQ10 can lower your blood pressure. High blood pressure can put you at risk for developing cardiovascular diseases prematurely. As such, controlling and lowering your blood pressure can help you avoid strokes, heart attacks, and other dangerous health problems.
Studies have supported CoQ10 being an effective treatment for hypertension (3). Hypertension is when your blood pressure is too high, and lowering this is vital for optimal circulation and heart health.
CoQ10 can help protect against developing degenerative diseases. CoQ10 is touted for its ability to protect your brain. Your brain is the control center of your body, and without proper brain health, all sorts of problems and diseases can emerge in your body.
One article published in 2009 showed that CoQ10 can protect you from Parkinson’s, Huntington’s, and Alzheimer’s disease (4). Another study cited that CoQ10 decreased amyloid pathology and helped improve mice with Alzheimer’s disease (5).
Another article cited CoQ10 benefits for Parkinson’s disease (6). Evidence also suggests that Alzheimer’s disease is caused by oxidative damage that is brought about by mitochondrial dysfunction. Research indicates that CoQ10 can be a good option for neurodegenerative disease (7). However, more conclusive evidence is needed to confirm.
CoQ10 can keep your skin youthful. Your skin not only affects how young and vibrant you look but also protects you from bacteria and free radicals. A study published in 2016 hinted that CoQ10 could play a vital role in skin protection. Specifically, the study noted that CoQ10 provides antioxidant effects to your skin and reduces free radicals (8).
Furthermore, low levels of CoQ10 were linked to melanoma progression (9). Melanoma is the worst kind of skin cancer, and getting enough CoQ10 is an excellent way to fight off this malevolent illness. As such, CoQ10 can help you maintain your youth well into your later years by protecting your skin.
CoQ10 may be able to help with age-related diseases. It’s not surprising that our body starts to deteriorate as we get older.
Since CoQ10 provides your body with a bunch of health benefits, including better brain health, heart health, skin health, and reduced risk of cancer, it’s a surefire way to keep your body young. In a study of 443 elderly individuals, each participant was given CoQ10, and it resulted in them needing less time in a hospital (10).
CoQ10 can help you reduce the risk of cancer. Studies show that low levels of CoQ are proven to increase the risk of breast cancer in Chinese women (11). Although cancer can show up in healthy individuals, it’s often a result of your body lacking proper nutrients. Moreover, another study revealed a substantial deficiency in CoQ10 in patients with cancer (12).
Prostate cancer is a notorious cancer that many men face as they get older. Thankfully, the right supplement can reduce men’s chances of getting it. CoQ10 shows promising effects for people with prostate cancer (13).
CoQ could reduce your muscle pain. Statin medications can cause unwanted side effects, such as asthenia or myalgia. Thankfully, CoQ10 has shown signs that it can help mitigate these symptoms. Patients taking statins that consumed CoQ10 for 3 months showed reduced myalgia (14).
Taking CoQ10 can also help you maintain good heart health by allowing you to continue to take a statin to reduce your cholesterol without any side effects.
CoQ10 may reduce headaches and migraines. Emotional triggers, such as stress and anxiety, can be a hidden culprit behind your migraines. Fatigue, lack of sleep, and overexerting yourself physically can all cause migraines too. Since these symptoms are common in our society, it’s not unusual for individuals to have a regular migraine.
Fortunately, CoQ10 can help with this. 1550 patients with frequent headaches or CoQ10 deficiency were tested and concluded that CoQ10 improves headaches and migraines (15). Another study published in Nutritional Neuroscience found that CoQ10 reduced migraines in patients (16).
Another 2018 meta-analysis showed that CoQ10 could alleviate migraines as well (17). Furthermore, the journal of Neurology issued a study on 42 migraine patients and found CoQ10 to be an effective protocol for migraines (18).
CoQ10 may play a role in increasing exercise performance. Interestingly enough, CoQ10 could be a natural performance enhancer that many don’t know about. One study demonstrates that CoQ10 can aid those with mitochondrial disorders, which can, in turn, help improve cellular energy output (19).
In another study, CoQ10 shows performance-enhancing effects during repeated bouts of supramaximal exercise (20). A 2008 study involving 17 volunteers receiving either 100 mg of CoQ10 per day or a placebo for 8 days showed slower fatigue time (21).
Moreover, a 14-day CoQ10 supplementation trial with trained and untrained individuals demonstrated that CoQ10 increases time to exhaustion (22).
CoQ10 could prevent diabetes. There are three main types of diabetes, type 1, type 2, and gestational. While some are hereditary, others can be avoided by following a healthy lifestyle. If you’re prone to suffering from diabetes, taking a promising supplement could be just what you need.
The Journal of the American College of Nutrition published a study in 2017 that found after 12 weeks of supplementing with CoQ10, insulin levels decreased in diabetic nephropathy patients (23).
Furthermore, another study involving 50 patients showed an improvement in glycemic control after consuming CoQ10 (24).
CoQ10 could improve your heart health. When you improve your heart health, your chances of suffering from serious health issues, like myocardial infarction and other heart diseases, significantly decrease. Eating a balanced diet and exercising for your heart health is of utmost importance, but a quality supplement could enhance it even more. Growing research is supporting that CoQ10 deficiency is linked with cardiovascular issues (25).
One study showed an improvement in cardiovascular symptoms and a reduction in chronic heart failure across 420 patients supplementing with CoQ10 (26).
A 2009 study also stated, “Significant improvement has been observed in clinical and hemodynamic parameters and exercises tolerance in patients given adjunctive CoQ10 in doses from 60 to 200 mg daily in various trials conducted in patients of heart failure, hypertension, ischemic heart disease, and other cardiac illnesses” (27).
CoQ10 may help with fertility. Maintaining good fertility is tied to your reproductive health, and if you plan on having a child, you must get this taken care of. According to one study, semen parameters increase when supplementing with CoQ10 (28).
Who should not take CoQ10? Taking CoQ10 could lower your blood pressure and blood sugar levels. It could also affect your enzyme levels if you take too much. As such, people suffering from chronic diseases, like heart failure, kidney issues, liver problems, or diabetes, should be careful about taking a CoQ10 supplement.
What is the best time to take CoQ10? The best time to take CoQ10 is in the morning or afternoon because taking it too close to bedtime could cause insomnia in some people.
Does CoQ10 reduce your oxidative stress? CoQ10 helps to improve your heart health and blood sugar regulation, can prevent cancer, and reduce the frequencies of migraines.
Furthermore, it can increase your workout performance by decreasing the oxidative stress that causes muscle fatigue, skin damage, brain disease, and lung disease. Since CoQ10 can be deficient in your body, especially if you’re older, this can be a powerful supplement for you.
How long does it take for CoQ10 to work? CoQ10 can take up to 12 weeks before you experience any benefits. CoQ10 is used for a multitude of reasons, including migraines, heart health, brain health, and skin health.
Is CoQ10 worth taking? Absolutely. CoQ10 is naturally produced in your body, but some people have lower amounts and may need to take a CoQ10 supplement. As you age and develop medical conditions, your CoQ10 levels will decrease.
Since CoQ10 plays a key role in a healthy body, you must make sure your body is getting enough of it. Although, if you have any chronic diseases, such as heart failure, kidney, or liver problems, it’s best to avoid it.
Does CoQ10 make you lose weight? CoQ10 doesn’t directly make you lose weight, but it does provide your body with a ton of health benefits that can then be taken advantage of to aid in weight loss.
If you plan to take CoQ10 for weight loss, make sure you’re exercising and eating healthy since this is the most important component of weight loss.
Is CoQ10 bad for the liver? CoQ10 could be bad for your liver if you consume too much of it. It’s recommended that you avoid taking more than 300mg per day.
What medications interact with CoQ10? Anticoagulant medication may interfere with CoQ10 because it could make blood-thinning medications, such as warfarin (Coumadin, Jantoven), less effective. This could increase your risk of blood clotting.
Is CoQ10 the same as fish oil? CoQ10 isn’t the same as fish oil, but some CoQ10 supplements contain both CoQ10 and fish oil. This is beneficial for your cardiovascular health.
Who should take CoQ10 supplements? People low in CoQ10, such as older adults, should take a CoQ10 supplement. This will help you improve muscular strength, vitality, and physical performance.
However, CoQ10 can be utilized by anyone since it produces an array of benefits, such as decreasing muscular pain, headaches, and even giving you more energy.
Does CoQ10 cause blood clots? Although CoQ10 doesn’t directly cause blood clots, it could if you’re taking a blood-thinning medication, such as warfarin (Coumadin, Jantoven).
Does CoQ10 give you gas? CoQ10 can give you diarrhea, although it’s rare. To avoid this, look at the CoQ10 and Ubiquinol review.
Is it okay to take CoQ10 every day? Yes, it’s safe to take CoQ10 every day. Taking at least 90-200 mg per day is recommended. Depending on your condition, you may need more, ranging from 300-600 mg.
How does CoQ10 make you feel? People report feeling more energized while taking CoQ10, but you should be wary of side effects, including an upset stomach, headaches, feeling jittery, or insomnia. You also should see a decrease in your blood pressure and improved skin health.
How much CoQ10 should I take daily? It’s typically recommended to take between 100-200 mg per day. However, there is no ideal amount. Some adults even take several does a day and can reach as high as 1200 mg.
Does CoQ10 make you gain weight? No, CoQ10 doesn’t make you gain weight. In fact, a deficiency could cause your metabolism to slow down since it helps your cell produce energy, which could make losing weight harder.
What is the best brand of CoQ10? The best brand of CoQ10 is Essential Elements. It absorbs 2.6X faster and significantly supports your brain, heart, and vascular system.
Can you take vitamin D with CoQ10? Yes, you can take vitamin D with CoQ10. There have been no known side effects of combining the two. Although, it’s always recommended to err on the side of caution and contact your physician first.
Does CoQ10 make you look younger? Yes, CoQ10 can make you look younger because it supports your collagen and elastin to keep your skin healthy and vibrant.
What does CoQ10 do for your skin? It supports the production of collagen to help alleviate signs of aging, such as fine lines and wrinkles.
Does CoQ10 speed up your metabolism? CoQ10 could speed up your metabolism, which is why it can help you with weight loss.
Can taking CoQ10 be harmful? CoQ10 is generally safe to take, and the side effects are usually rare and mild. If you have a chronic disease like heart failure, kidney, liver problems, or diabetes, you should be careful when using this supplement.
Does CoQ10 raise cholesterol? CoQ10 could raise your cholesterol because it’s shown that those with low levels of CoQ10 often have low levels of good cholesterol.
Does CoQ10 raise blood pressure? No, CoQ10 doesn’t raise your blood pressure, but it can lower your blood pressure.
What foods are high in CoQ10? Meats, fish, vegetables, fruits, and legumes are high in CoQ10. Specifically, pork, beef, chicken, trout, herring, mackerel, sardine, spinach, cauliflower, broccoli, oranges, strawberries, soybeans, lentils, and peanuts.
Does CoQ10 lower cholesterol? Taking CoQ10 could lower your bad LDL cholesterol.
Is it good to take CoQ10 with statins? Yes, it’s good to CoQ10 with statins since statins has been found to lower the natural amounts of CoQ10 your body produces.
What does CoQ10 do for the heart? CoQ10 may reduce your risk of experiencing a heart attack. It can also improve outcomes in patients with heart failure, lower blood pressure, and repel the side effects of statin, which lowers cholesterol.
Can CoQ10 prevent a heart attack? Yes, CoQ10 can lower your risk of a heart attack.
Is CoQ10 good for your kidneys? Patients with chronic kidney disease can lower their plasma concentrations of CoQ10, so CoQ10 is good for your kidneys if you suffer from kidney disease.
Does CoQ10 have quinine in it? CoQ10 is related to ubiquinols, which are structurally similar to quinine. If you’re allergic to quinine, you should speak to a medical practitioner before starting a CoQ10 supplement.
Is CoQ10 hard on your stomach? Most people don’t have any issues with their stomach when taking CoQ10. However, it can cause some mild side effects, including an upset stomach, loss of appetite, nausea, vomiting, and diarrhea.
Is Kirkland CoQ10 good quality? Kirkland made our list because it has no artificial ingredients and contains a high dose. It is considered to be good quality.
Does CoQ10 give you energy? Yes, it’s a compound that helps you generate energy in your cells, which gives you a boost of energy.
What are the symptoms of low CoQ10? There is a wide variety of symptoms for people with low CoQ10, with the most serious ones being brain dysfunction, muscle weakness, and the failure of other major body systems.
Is 400 mg of CoQ10 too much? Typically, 90-200 mg is recommended, but some people require higher doses and consume 300-600 mg.
Is CoQ10 a blood thinner? CoQ10 isn’t a blood thinner, but it could reduce the effectiveness of blood-thinning medications, such as warfarin.
Can CoQ10 keep you awake at night? For most people, this won’t be a problem, but it could cause insomnia.
Can CoQ10 cause depression? No, CoQ10 won’t cause depression. It could help people with depressive symptoms.
Is CoQ10 good for hair growth? CoQ10 could potentially be good for hair loss by stimulating the gene expression of different hair keratins.
Is CoQ10 good for wrinkles? Yes, since CoQ10 is good for your skin health, it can reduce wrinkles. It does this by providing your skin with energy and supporting collagen production.
Is quercetin the same as CoQ10? Quercetin and CoQ10 aren’t the same, but they both help protect cells from oxidative damage by reactive oxygen species (ROS).
Is Nature Made CoQ10 a good brand? Yes, Nature Made is a quality brand of CoQ10, which is why it made our top ten ranking list. It’s perfect if you’re a statin user to replace the loss in CoQ10.
How much CoQ10 should I take? It varies from individual to individual, but it’s recommended you take 100-200 mg per day. However, some people take much more ranging from 300-600 mg to even upwards of 1200 mg.
Can you take CoQ10 with high blood pressure medication? Since CoQ10 can help lower blood pressure, taking CoQ10 may allow you to reduce your blood pressure medicine prescription. However, you should consult a medical provider first.
What age should you start taking CoQ10? Adults 19 years and older have the green light to take CoQ10 medicine. However, it’s recommended for older individuals since you produce less of it as you age.
How much CoQ10 should I take for muscle cramps? For muscle cramps, you should take 100-200 mg daily.
Does CoQ10 help nerve damage? Because CoQ10 is a strong antioxidant, it can prevent neural tissue damage from oxidative stress, and help to reduce the expression of pro-inflammatory factors that attenuate neuropathic pain behavior.
Can I take CoQ10 with fish oil? Yes, taking CoQ10 with fish oil makes an excellent combo. It will give you the benefits of each supplement while at the same time, enhance CoQ10 absorption.
Does CoQ10 reduce inflammation? CoQ10 can reduce inflammation of the lungs.
Where do you get CoQ10 naturally? You can naturally get CoQ10 from oily fish, organ meats, and whole grains.
Do I need CoQ10 if I’m not on statins? Taking CoQ10 is good while you’re on statins since statin naturally reduces your body’s production of CoQ10. Although, even if you’re not on statins, CoQ10 provides your body with a host of benefits.
How much CoQ10 should you take if you are taking statins? If you’re taking statins, it’s recommended you take 30-200 mg per day.
CoQ10 is a potent nutrient that your body requires for maintaining optimal cellular and cardiovascular health. Without sufficient CoQ10 levels, you may be at risk for a variety of diseases, including migraines, heart failure, and Alzheimer’s.
CoQ10 is difficult to obtain from your diet, supplementation becomes very important.
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